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Bioplastics

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Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...

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Updated: Apr 8, 2026

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

A Hierarchically Structured, Stretchable, Anti-Biofouling Encapsulation for Biodegradable Electronics.

Won Bae Han^1,2, Sungkeun Han¹, Gwan-Jin Ko^1,3

¹KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, 02841, Republic of Korea.

Advanced Healthcare Materials

|September 23, 2025

Summary

This summary is machine-generated.

Researchers developed a novel anti-biofouling encapsulant for biodegradable implants. This innovation improves device longevity and biocompatibility by preventing unwanted cell adhesion and tissue formation in aqueous environments.

Keywords:

anti‐biofouling biodegradable electronics encapsulation hierarchical structure superhydrophobic

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Last Updated: Apr 8, 2026

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

A Simple and Scalable Fabrication Method for Organic Electronic Devices on Textiles

A Simple and Scalable Fabrication Method for Organic Electronic Devices on Textiles

Published on: March 13, 2017

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Published on: October 20, 2018

Area of Science:

Biomaterials Science
Polymer Chemistry
Nanotechnology

Background:

Biodegradable polymers are used for transient implantable devices.
Existing polymers lack anti-biofouling properties, causing issues like protein adsorption and fibrotic encapsulation.
This compromises device function and biocompatibility, especially for long-term use.

Purpose of the Study:

To engineer a soft, stretchable, and anti-biofouling encapsulant for biodegradable implants.
To enhance the performance and biocompatibility of transient electronic devices.

Main Methods:

Integrating self-assembled organosilicon nanowire networks onto micropatterned biodegradable elastomers.
Creating a hierarchical surface architecture for superhydrophobicity.
Testing the encapsulant in transient, stretchable optoelectronic devices.

Main Results:

Achieved superhydrophobicity while maintaining mechanical integrity and stability under strain.
Improved water barrier performance by up to 420% compared to unmodified films.
Demonstrated suppressed cell adhesion, reduced fibrotic tissue formation, and excellent biocompatibility in vitro and in vivo.

Conclusions:

The developed encapsulant offers superior anti-biofouling properties and enhanced water barrier performance.
Integration into devices enables prolonged operation in aqueous environments.
Highlights potential for developing long-lasting, bioresorbable electronic implants with improved biocompatibility.