Percutaneous closure of a large left main coronary artery fistula in a paediatric patient

Manuela da Silva Lopes1, Diogo Faim1, Patrícia Vaz Silva1

  • 1Department of Paediatric Cardiology and Referral Center for Congenital Cardiac Defects, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.

Cardiology in the Young
|September 23, 2025
PubMed

Insights

A large left coronary artery fistula was successfully closed in a child using a minimally invasive percutaneous technique with an Amplatzer Vascular Plug II. This interventional cardiology approach offers a new treatment option for complex congenital heart defects.

Area of Science:

  • Interventional Cardiology
  • Pediatric Cardiology
  • Congenital Heart Disease

Background:

  • Coronary artery fistulas are abnormal connections between a coronary artery and a cardiac chamber or vessel.
  • Large coronary artery fistulas in children can lead to significant complications, including heart failure and pulmonary hypertension.
  • Percutaneous closure is a less invasive alternative to surgical repair for selected cardiac defects.

Purpose of the Study:

  • To report the successful percutaneous closure of a large left coronary artery fistula in a pediatric patient.
  • To evaluate the efficacy and safety of using an Amplatzer Vascular Plug II for this indication.
  • To highlight the potential of interventional cardiology in managing complex congenital coronary anomalies.

Main Methods:

  • A large left coronary artery fistula was identified in a pediatric patient.
  • Percutaneous closure was performed using an Amplatzer Vascular Plug II.
  • Access was gained through an arteriovenous loop, facilitating device deployment.

Main Results:

  • The Amplatzer Vascular Plug II was successfully deployed, achieving complete closure of the fistula.
  • The procedure was technically successful with no immediate complications.
  • The patient tolerated the intervention well, with favorable short-term outcomes.

Conclusions:

  • Percutaneous closure with an Amplatzer Vascular Plug II is a safe and effective treatment for large coronary artery fistulas in children.
  • The arteriovenous loop approach provides a viable route for device delivery in complex cases.
  • Interventional cardiology offers a valuable therapeutic option for pediatric patients with coronary artery fistulas.