Related Experiment Video
Updated: Jul 7, 2026

28:13
Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
33.9K
Hybrid one-stage atrial fibrillation ablation
Raymond Pfister1, Jorge Alcocer1, Stefano Italiano1
1Department of Cardiothoracic Surgery, Hospital Clinic, University of Barcelona, Barcelona, Spain
Multimedia Manual of Cardiothoracic Surgery : MMCTS
|September 23, 2025
Summary
Hybrid ablation offers improved outcomes for persistent atrial fibrillation (AF) when endocardial catheter ablation (CA) alone is insufficient. This technique combines epicardial and endocardial ablation for better results.
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- Persistent and long-standing persistent atrial fibrillation (AF) significantly impact patient quality of life and are linked to adverse health outcomes.
- Endocardial catheter ablation (CA) monotherapy demonstrates limited efficacy in managing these complex AF types.
- Hybrid ablation strategies, integrating epicardial and endocardial approaches, show promise for improved AF treatment.
Purpose of the Study:
- To illustrate a hybrid ablation technique for persistent and long-standing persistent atrial fibrillation.
- To detail a combined epicardial and endocardial ablation strategy.
- To showcase left atrial appendage exclusion and ablation of specific atrial regions.
Main Methods:
- The described hybrid technique involves left atrial dome ablation and left atrial appendage exclusion via left thoracotomy.
- Posterior left atrial wall ablation is performed using a subxiphoid approach.
- Endocardial catheter ablation (CA) is completed during the same procedural session.
Main Results:
- The hybrid approach aims to improve upon the limited efficacy of endocardial CA alone.
- Combining epicardial and endocardial ablation, including LAA exclusion, has demonstrated enhanced outcomes in preliminary studies.
- This procedural video serves as a tutorial for a comprehensive hybrid AF ablation strategy.
Conclusions:
- Hybrid ablation, incorporating epicardial and endocardial techniques, represents an advanced strategy for treating challenging persistent atrial fibrillation.
- Left atrial appendage exclusion and targeted ablation regions are key components of this improved approach.
- This combined method offers a potential solution for patients with limited response to conventional catheter ablation.

