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Genetic Pseudocholinesterase Deficiency Unmasked After Succinylcholine-Rivastigmine Interaction: A Case Report

Edward Ho1, Brett Simpson2, Natalie Anne Smith1

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|September 23, 2025
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Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
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