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Published on: September 13, 2018
Feline leukaemia virus subgrouping using a viral interference assay
Dimas Arya Abdillah1,2, Takahiro Hiratsuka1, Fumiko Matsuyama3
1Laboratory of Molecular Immunology and Infectious Disease, Joint Graduate School of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, 753-8515, Yamaguchi, Japan.
Abstract:
Feline leukaemia virus subgroup A (FeLV-A) is transmitted among cats, and FeLV subgroups are frequently generated de novo. We investigated the frequency of detection of subgroups using interference assays in 50 cases. FeLV-A infection alone was detected in 38% of the cases, whereas coinfection with both FeLV-A and FeLV-B was observed in 62% of the cases. No cases of FeLV-B infection alone were observed. Cases of coinfection with FeLV-A and FeLV-B showed a higher prevalence than cases of FeLV-A infection alone. The FeLV containing an X region was discovered in two new cases. This study may help to elucidate the mechanism underlying FeLV-B-associated diseases.
