Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Thin-Walled Hollow Shafts01:15

Thin-Walled Hollow Shafts

508
In analyzing a thin-walled hollow shaft subjected to torsional loading, a segment with width dx is isolated for examination. Despite its equilibrium state, this segment faces torsional shearing forces at its ends. These forces are quantitatively described by the product of the longitudinal shearing stress on the segment's minor surface and the area of this surface, leading to the concept of shear flow. This shear flow is consistent throughout the structure, indicating a uniform distribution of...
508

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advanced polymers for kidney and urinary tract tissue engineering.

Tissue & cell·2026
Same author

Mediolateral and anteroposterior balance control during Sit-to-Stand in individuals with transfemoral amputation.

Journal of biomechanics·2026
Same author

Comparing the effect of off-loading knee brace with and without local muscle vibration on clinical and biomechanical outcomes in patients with medial knee osteoarthritis: A randomized clinical trial.

Journal of rehabilitation and assistive technologies engineering·2026
Same author

Osseointegration dynamics of mandibular patient-specific implants: A mechanoregulation-based finite element study.

The Journal of prosthetic dentistry·2026
Same author

Exploring the anticancer potential of epigallocatechin gallate-loaded sodium alginate nanoparticles: impact of size variation on head and neck cancer cells.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2026
Same author

Biogenic hydroxyapatite-zinc oxide nanocomposites: A synergistic strategy for antibacterial and osteoconductive coatings on orthopedic implants.

Heliyon·2026

Related Experiment Video

Updated: Jan 6, 2026

Additive Manufacturing of Functionally Graded Ceramic Materials by Stereolithography
06:53

Additive Manufacturing of Functionally Graded Ceramic Materials by Stereolithography

Published on: January 25, 2019

15.0K

Conceptual Design and Additive Manufacturing of a Bidirectional Gradient Gyroid Structure for Tibial Stem.

Atiyeh Taheri1,2, Farzam Farahmand3, Marjan Bahraminasab4

  • 1Mechanical Engineering Department, Sharif University of Technology, Tehran, Iran.

Annals of Biomedical Engineering
|September 23, 2025
PubMed
Summary

Bidirectional gradient lattice structures for total knee replacement tibial stems show promise for enhancing bone remodeling and osteogenic response. This additive manufacturing approach offers patient-specific solutions for improved implant fixation and longevity.

Keywords:
Bone remodelingMicromotionSelective laser meltingTotal knee replacement

More Related Videos

4D Printed Bifurcated Stents with Kirigami-Inspired Structures
06:52

4D Printed Bifurcated Stents with Kirigami-Inspired Structures

Published on: July 25, 2019

8.4K
Multi-material Ceramic-Based Components – Additive Manufacturing of Black-and-white Zirconia Components by Thermoplastic 3D-Printing (CerAM - T3DP)
08:29

Multi-material Ceramic-Based Components – Additive Manufacturing of Black-and-white Zirconia Components by Thermoplastic 3D-Printing (CerAM - T3DP)

Published on: January 7, 2019

11.8K

Related Experiment Videos

Last Updated: Jan 6, 2026

Additive Manufacturing of Functionally Graded Ceramic Materials by Stereolithography
06:53

Additive Manufacturing of Functionally Graded Ceramic Materials by Stereolithography

Published on: January 25, 2019

15.0K
4D Printed Bifurcated Stents with Kirigami-Inspired Structures
06:52

4D Printed Bifurcated Stents with Kirigami-Inspired Structures

Published on: July 25, 2019

8.4K
Multi-material Ceramic-Based Components – Additive Manufacturing of Black-and-white Zirconia Components by Thermoplastic 3D-Printing (CerAM - T3DP)
08:29

Multi-material Ceramic-Based Components – Additive Manufacturing of Black-and-white Zirconia Components by Thermoplastic 3D-Printing (CerAM - T3DP)

Published on: January 7, 2019

11.8K

Area of Science:

  • Biomaterials Engineering
  • Orthopedic Biomechanics
  • Additive Manufacturing

Background:

  • Additive manufacturing enables cellular lattice structures for orthopedic implants.
  • Gradient porosity in implants can improve biomechanical performance and reduce aseptic loosening.
  • Previous designs were limited to unidirectional gradients.

Purpose of the Study:

  • To conceptually design bidirectional graded lattice structures for total knee replacement (TKR) tibial stems.
  • To enhance osteogenic response and periprosthetic bone remodeling.
  • To optimize gradient parameters for improved implant integration.

Main Methods:

  • Multi-objective optimization using a design of experiment approach.
  • Development of three finite element models (preoperative, early, late postoperative TKR).
  • Application of a computational mechanobiology framework to predict osseointegration and bone remodeling.

Main Results:

  • Five optimal graded lattice structures were identified for different patient groups.
  • An axially graded structure (20% density) promoted osteogenesis in older patients.
  • A radially graded structure (10% density) reduced bone resorption in younger adults.
  • An optimal bidirectional gradient structure (27% radial, 73% axial, 10% density) enhanced bone remodeling.
  • SEM confirmed manufacturability of graded gyroid specimens with minor fabrication errors.

Conclusions:

  • Computational and experimental findings support the benefits of bidirectional graded tibial stems.
  • The study demonstrates the manufacturability of these advanced implant designs.
  • Bidirectional gradient structures offer a promising approach for enhancing TKR implant outcomes.