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Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
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Updates in endoscopic hemostasis for nonvariceal gastroduodenal bleeding
Himesh B Zaver1, Mary S McGrath, Andrew Y Wang
1Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.
Current Opinion in Gastroenterology
|September 23, 2025
Summary
Updated guidelines for nonvariceal upper gastrointestinal bleeding management highlight early risk assessment and advanced endoscopic hemostasis techniques. A multidisciplinary approach ensures optimal patient outcomes.
Area of Science:
- Gastroenterology
- Endoscopic Procedures
Background:
- Nonvariceal upper gastrointestinal bleeding (NVUGIB) remains a significant clinical challenge.
- Current management strategies are evolving with new research and technological advancements.
Purpose of the Study:
- To present an updated overview of NVUGIB management.
- To focus on recent progress in endoscopic hemostasis and evidence-based practices.
Main Methods:
- Review of recent studies and societal guidelines.
- Analysis of advancements in endoscopic hemostasis modalities.
- Integration of risk stratification tools and clinical practices.
Main Results:
- Emphasis on early triage and restrictive transfusion strategies for NVUGIB.
- Introduction of cap-assisted clips, noncontact thermal therapies, and novel topical hemostatic agents.
- Importance of risk stratification tools in guiding NVUGIB management.
Conclusions:
- Effective NVUGIB management necessitates a multidisciplinary approach.
- Prioritizing early resuscitation and risk assessment is crucial.
- Evolving endoscopic technologies are key to achieving optimal hemostasis in NVUGIB.
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