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Updated: Jan 17, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
Updates in endoscopic hemostasis for nonvariceal gastroduodenal bleeding
Himesh B Zaver1, Mary S McGrath, Andrew Y Wang
1Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.
Purpose Of Review:
To provide an updated overview of the management of nonvariceal upper gastrointestinal bleeding, focusing on recent advancements in endoscopic hemostasis techniques and evidence-based clinical practices.
Recent Findings:
Recent studies and societal guidance emphasize the importance of early triage, restrictive transfusion strategies, and the integration of risk stratification tools for management of nonvariceal upper gastrointestinal bleeding. Notable advancements in endoscopic modalities for hemostasis include cap-assisted clips, noncontact thermal therapies, and the expansion of available topical hemostatic agents.
Summary:
Effective nonvariceal upper gastrointestinal bleeding management requires a multidisciplinary approach that prioritizes early resuscitation, risk assessment, and the use of evolving endoscopic technologies to achieve optimal hemostasis.
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