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Widespread Transduction of Mouse Neocortical Neurons by Subarachnoid Injection of AAV2
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Old World alphaviruses use distinct mechanisms to infect brain microvascular endothelial cells for neuroinvasion

Pablo A Alvarez1, Ashley Tang2, Declan M Winters3

  • 1Department of Microbiology, Immunology, & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Cell Reports
|September 23, 2025
PubMed

Keywords:
CP: Microbiologyalphavirusblood-brain barrierbrain microvascular endothelial cellshuman pluripotent stem cell-derived modelneuroinvasionvirus entryvirus receptor

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