Relational model of all genetic codes
Nikola Štambuk1, Paško Konjevoda2, Albert Štambuk3
1Center for Nuclear Magnetic Resonance, Ruđer Bošković Institute, Bijenička cesta 54, HR-10000, Zagreb, Croatia.
Abstract:
The most common way to display the rules of all genetic codes is the Standard Genetic Code (SGC) table and its variants. This article takes an alternative approach to the genetic code table based on the relational model (Konjevoda and Štambuk, 2021). The relational model (RM) proposes distributed storage of the data into a collection of tables, which are called relations. Basic elements of the SGC table are rows (called records or tuples) and columns (called attributes). The SGC table, according to the RM, represents the so-called unnormalized form of a table, and it can be decomposed or divided into 4 tables using a set of rules called normal forms. The rows and columns of a single table are defined by the first and second base, and individual tables are specified by the third codon base. The result of this model is an approach to managing genetic code data, represented in terms of tuples and grouped into relations, with table structure and language consistent with the first-order logic, and sixteen truth functions defined by IUPAC ambiguity codes for incomplete nucleic acid specification. It is concluded that the relational model is a suitable method to display the rules of the Standard Genetic Code and its 28 variants according to Marcello Barbieri's concepts of ambiguity reduction and codepoiesis.
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