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Updated: Jan 17, 2026
Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
The Association Between Salivary Function and Laryngopharyngeal Reflux Measured Objectively
So Young Jeon1, Hwa Sung Rim1, Yeonseo Lee2
1Department of Otolaryngology-Head & Neck Surgery, Kyung Hee University School of Medicine, Kyung Hee University Medical Center, Seoul, Korea.
Objective:
To evaluate the association between salivary function measured by salivary flow rate (SFR) and laryngopharyngeal reflux (LPR) in patients with symptoms completed 24-hour hypopharyngeal-esophageal multichannel intraluminal impedance-pH (24-h-HEMII-pH) monitoring.
Methods:
Patients with LPR symptoms underwent the 24-h-HEMII-pH monitoring and SFR was measured. We compared the SFR differences between LPR and non-LPR groups.
Results:
Sixty-seven of 80 (84%) patients were diagnosed with LPR. The mean unstimulated SFR of the LPR and non-LPR groups was 0.48 and 0.52 mL/min (P = 0.735). The mean stimulated SFR of the LPR and non-LPR groups was 2.5 and 2.3 mL/min (P = 0.610). In the LPR group and non-LPR group, the reflux symptom index (RSI) of the normal and abnormal SFR groups was not significantly differnt (P = 0.27 and P = 0.454).
Conclusions:
There was no significant difference in salivary function between patients with LPR and non-LPR.
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