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DCDSN: dual-color domain siamese network for multi-classification of pathological artifacts
Wei-Long Ding1, Jin-Long Liu1, Wei Zhu1
1College of Computer Science and Technology, Zhejiang University of Technology, Hangzhou, 310023, People's Republic of China.
Biomedical Physics & Engineering Express
|September 24, 2025
Summary
This study introduces a Dual-Color-Domain Siamese Network (DCDSN) for robust pathological artifact detection. The DCDSN improves accuracy and significantly reduces computational costs, enhancing diagnostic reliability.
Area of Science:
- Digital Pathology
- Medical Image Analysis
- Artificial Intelligence in Medicine
Background:
- Pathological image artifacts compromise diagnostic accuracy.
- Existing artifact detection methods face challenges with variability, high computational costs, and limited color perception, especially in Hematoxylin-Eosin (H&E) stained images.
- Single-color domain reliance hinders distinguishing artifacts from normal tissue.
Purpose of the Study:
- To develop a robust and efficient method for pathological artifact detection.
- To enhance feature representation and color perception in pathological images.
- To reduce the computational burden of artifact detection systems.
Main Methods:
- Proposed a Dual-Color-Domain Siamese Network (DCDSN) leveraging RGB and HSV color domains.
- Employed Siamese network similarity learning to minimize representation discrepancies between color domains.
- Integrated a lightweight MobileViT-XS backbone with transfer learning for efficiency.
- Introduced a Dynamic Snake Convolution-based feature mapper to improve sensitivity to subtle artifact features.
Main Results:
- The DCDSN achieved 90.97% accuracy, outperforming the AR-Classifier baseline.
- Significantly reduced parameter counts (74.39%) and computation (96.55%).
- Demonstrated strong performance with lower resource consumption.
Conclusions:
- The DCDSN effectively detects artifacts in pathological images with high accuracy and efficiency.
- Leveraging dual color domains and a lightweight architecture enhances feature representation and reduces computational cost.
- The proposed method offers a promising solution for improving pathological image quality and diagnostic reliability.

