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Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models
Published on: January 5, 2024
Incidental Ovarian Vein Thrombosis During Breast Cancer Therapy With Tamoxifen and Trastuzumab
Jorge Illarramendi1, Susana Mauleon2, Helena Sarasibar2
1Hematology, Hôpital Haut-Lévêque, Pessac, FRA.
Abstract:
Ovarian vein thrombosis (OVT) is an unusual presentation of venous thromboembolic disease. Incidental asymptomatic appearance of OVT is a recognized complication of gynecologic cancer surgery, but published information on incidental OVT during targeted therapy of cancer with hormone therapy and/or monoclonal antibodies is scarce. We present the case of a 41-year-old woman who had a diagnosis of asymptomatic right OVT during the adjuvant treatment of breast cancer with tamoxifen plus trastuzumab. Clinical evolution in this case was favorable without anticoagulant therapy, with confirmed thrombus resolution and without further events. Available literature on this topic is limited, but some data indicate that anticoagulation is also a valuable option to consider, according to potential advantages and risks, on an individual basis.
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