Related Experiment Video

Updated: Jun 19, 2026

Establishing a Liquid-covered Culture of Polarized Human Airway Epithelial Calu-3 Cells to Study Host Cell Response to Respiratory Pathogens In vitro
12:09

Establishing a Liquid-covered Culture of Polarized Human Airway Epithelial Calu-3 Cells to Study Host Cell Response to Respiratory Pathogens In vitro

Published on: February 7, 2013

23.0K

Factors associated with hospital-acquired Candida auris in a DC hospital

Joanne Dietrich1, Tara Millson1

  • 1MedStar Georgetown University Hospital's Infection Prevention and Control, Washington, DC, USA.

Antimicrobial Stewardship & Healthcare Epidemiology : ASHE
|September 24, 2025
PubMed

Insights

A Washington D.C. hospital saw more hospital-acquired Candida auris infections. Targeted interventions reduced infection rates and outbreak risks.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Healthcare Epidemiology

Background:

  • A significant rise in hospital-acquired (HA) *Candida auris* infections was observed at a Washington D.C. teaching hospital between August 2021 and July 2024.
  • This increase posed a substantial threat to patient safety and hospital resources.

Purpose of the Study:

  • To investigate the contributing factors behind the escalating HA *Candida auris* cases.
  • To implement and evaluate targeted interventions aimed at curbing the spread of *Candida auris*.

Main Methods:

  • Epidemiological data analysis to identify trends and potential sources of HA *Candida auris*.
  • Implementation of specific infection control and prevention strategies.
  • Monitoring of HA case rates and outbreak indicators post-intervention.

Main Results:

  • The implemented interventions led to a measurable reduction in the monthly HA *Candida auris* case rate.
  • The likelihood of a widespread outbreak was significantly decreased.

Conclusions:

  • Multifaceted interventions are effective in controlling HA *Candida auris* outbreaks in hospital settings.
  • Continued surveillance and prompt action are crucial for managing endemic *Candida auris*.

More Related Videos

Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation14:46

Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation

Published on: January 20, 2018

8.2K
Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure05:34

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure

Published on: December 13, 2024

1.1K

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...