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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Level of self-confidence among nurse practitioners in rural public health facilities regarding antimicrobial
Ziyanda Nzayini1, Andile Dlungele1, Lehlohonolo John Mathibe1
1Division of Pharmacology (Therapeutics), Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Durban 4013, South Africa.
Background:
Nurse practitioners, especially in remote rural areas in low- and middle-income countries, initiate treatment for numerous conditions including therapy against infections. For a sustained and meaningful reduction in antimicrobial resistance, nurse practitioners should confidently play a greater role as stewards of antibiotic therapy. Therefore, this study investigated the self-confidence level, perceptions, and professional development needs of nurse practitioners as stewards of antibiotic therapy in remote countryside areas in KwaZulu-Natal, South Africa.
Methods:
Data collection took place at six healthcare facilities in rural areas in KwaZulu-Natal, South Africa. Questionnaires, with open-ended and 5-point Likert-scale-based items, were distributed to nurse practitioners employed, ie, participants, at the research sites.
Results:
One hundred and thirty (n = 130) participants filled and returned questionnaires; 31% (n = 41) and 69% (n = 89) were males and females, respectively. Over 64% (n = 83) of nurse practitioners were not aware of the extent of inappropriate utilization of antibiotics in South Africa, with a median of 3 (interquartile range (IQR 2-3). Over 70% (n = 91) of participants knew that inappropriate utilization of antimicrobials was harmful to patients, with a median of 4 (IQR 3-5). Only 30% (n = 39) of participants felt confident enough to play a meaningful role as stewards of antimicrobial therapy.
Conclusions:
There is a need for continuous professional development programs on antimicrobial stewardship to enhance self-confidence among nurse practitioners in rural areas.
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