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Updated: Jan 17, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
39.4K
A Review on Current Challenges and Emerging Therapies in Psoriasis Management
Ashish Kumar Parashar1, Keshav Saini1, Vandana Arora Sethi1
1Lloyd Institute of Management and Technology, Plot No.-11, Knowledge Park-II, Greater Noida, 201306, India.
Reviews on Recent Clinical Trials
|September 24, 2025
Summary
Psoriasis management is improving with new therapies like interleukin-23 inhibitors and personalized medicine. These advancements aim to overcome treatment limitations and enhance patient outcomes for chronic psoriasis.
Area of Science:
- Dermatology
- Immunology
- Pharmacology
Background:
- Psoriasis is a chronic inflammatory skin disease with management challenges.
- Current treatments have limitations including side effects, resistance, cost, and variable responses.
Purpose of the Study:
- To review recent advancements in psoriasis management.
- To highlight novel therapeutic agents and personalized treatment strategies.
Main Methods:
- Review of emerging therapies targeting specific pathways (e.g., IL-23 inhibitors).
- Exploration of small molecule inhibitors (RORγt, ROCK2).
- Discussion of combination regimens, advanced topical delivery systems (microneedles, nanoparticles), and multi-omics approaches.
Main Results:
- Novel biologics like lebrikizumab show superior efficacy.
- Small molecule inhibitors expand therapeutic options.
- Biomarkers and multi-omics enable personalized treatment strategies.
Conclusions:
- Emerging therapies and personalized approaches offer significant promise for improving psoriasis management.
- Collaboration is key to translating scientific advancements into clinical practice for better patient outcomes.
Keywords:
PsoriasisRORγt and ROCK2 inhibitors.microneedlesmirikizumabnanoparticletopical drug deliveryMore Related Videos
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