An Iteratively Adapted Transdiagnostic Prevention Program for Diverse High School Settings (U-PEACE): Protocol for a...

Area of Science:

• Adolescent mental health
• Implementation science
• Evidence-based treatments

Background:

• Many adolescents face mental health challenges but lack access to evidence-based treatments (EBTs).
• Marginalized communities experience magnified disparities in mental healthcare access.
• Adapting existing EBTs for scalability in school settings is crucial.

Purpose of the Study:

• To iteratively adapt and implement the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents in Title 1 high schools.
• To focus on the feasibility and scalability of the intervention within diverse high school environments.
• To enhance accessibility of mental health support for adolescents.

Main Methods:

• Qualitative feedback from high school communities informed initial adaptations.
• An open-trial pilot case series assessed the feasibility of the adapted program: Unified Protocol for Emotional and Academic Challenges in Education.
• A randomized controlled trial will compare the adapted program to usual mental health services, using mixed methods and cost-effectiveness analyses.

Main Results:

• Data collection concluded in May 2025.
• Primary outcome analyses are anticipated by August 2025.
• Preliminary feasibility and effectiveness data will inform final adaptations.

Conclusions:

• The adapted protocol shows promise for guiding youth EBT adaptation in accessible, diverse settings.
• This intervention could become a valuable prevention program for adolescents with emotional concerns.
• The study contributes to scalable mental health solutions for youth.