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Updated: Jan 17, 2026

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
Published on: November 30, 2022
Time-frequency domain prior constrained deep unfolding network for low-dose CT reconstruction
Xiong Zhang1, Xinbo Zhang1, Xinzhong Li2
1Taiyuan University of Science and Technology, Tai yuan, China.
Background:
Low-dose computed tomography (LDCT) effectively reduces the risk of malignant disease; however, reducing the radiation dose introduces additional noise and stripe artifacts in the CT imaging process. While Convolutional Neural Networks (CNN) have demonstrated performance advantages in LDCT imaging tasks, their end-to-end network architecture limits adaptability to CT reconstruction tasks, leaving room for further performance improvement.
Objective:
To propose a low-dose CT reconstruction network based on the iterative algorithms, incorporating an interpretable network architecture to achieve superior reconstruction performance.
Methods:
To better adapt to CT reconstruction tasks, we proposed an interpretable deep unfolding network leveraging time-frequency and image domain priors to fully exploit the features extracted in the transform domain. The iterative optimization process of the proposed algorithm is mapped into a deep unfolding network, and a Stage Information Memory Network (SIMN) is designed to address information loss between adjacent stages and within each stage.
Results:
Experimental results on Mayo and Piglet datasets show that the proposed model outperforms state-of-the-art techniques in both quantitative metrics and visual quality.
Conclusions:
The proposed network effectively removes artifacts and noise from low-dose CT images, achieving excellent reconstruction performance.
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