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Photobiomodulation Therapy for Accelerating Soft Tissue Anesthesia Reversal and Preventing Self-Inflicted Injuries in
Mohammad Noroozian1,2, Rozhina Jalalian3, Reza Fekrazad4,5
1Department of Oral and Maxillofacial Surgery, School of Dentistry, Azad University of Medical Sciences, Tehran, Iran.
Photobiomodulation, Photomedicine, and Laser Surgery
|September 24, 2025
Summary
Photobiomodulation therapy (PBMT) significantly reduces prolonged soft tissue anesthesia duration in children undergoing dental procedures. However, its effectiveness in preventing soft tissue injury requires further investigation.
Area of Science:
- Pediatric Dentistry
- Biophotonics
- Regenerative Medicine
Background:
- Prolonged soft tissue anesthesia (STA) following pediatric dental treatments increases the risk of soft tissue injury (STI).
- Photobiomodulation therapy (PBMT) utilizes light energy to stimulate cellular processes, potentially mitigating adverse effects.
- A systematic review is needed to evaluate PBMT's efficacy in pediatric dental applications.
Purpose of the Study:
- To systematically review the existing literature on the role of PBMT in reducing STA duration.
- To assess the impact of PBMT on the incidence of STI after dental procedures in children.
- To synthesize evidence regarding PBMT's safety and effectiveness in pediatric dentistry.
Main Methods:
- Systematic review conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
- Included studies focused on pediatric patients (ages 4-10) receiving PBMT (diode laser, various parameters) post-dental treatment.
- Data extraction focused on STA duration and STI incidence.
Main Results:
- Five studies involving 32-60 participants were analyzed.
- PBMT demonstrated a statistically significant reduction in STA duration across all included studies (p < 0.05).
- The effect of PBMT on reducing the incidence of STI was inconclusive across the reviewed studies.
Conclusions:
- PBMT appears to be a safe and effective adjunctive therapy for reducing STA duration in pediatric dentistry.
- Further high-quality research is necessary to definitively establish PBMT's role in preventing STI in this population.
- The findings suggest PBMT is a promising, painless intervention for improving pediatric dental patient outcomes.

