Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

1.0K
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
1.0K
Feedback Inhibition00:46

Feedback Inhibition

56.8K
Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
56.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differential alterations in peripheral tryptophan pathways in methamphetamine versus MDMA users are linked to their contrasting psychiatric symptoms.

Translational psychiatry·2026
Same author

Dose-Dependent Effects of Catecholaminergic Modulation on Interference Control: Role of Baseline GABA and Glx in Cortico-Subcortical Networks.

Human brain mapping·2025
Same author

Memory deficits of MDMA users are linked to cortical thinning related to 5-HT receptor densities.

Brain : a journal of neurology·2025
Same author

On the role of the insula cortex in inhibitory control: insights from alpha and theta directed connectivity dynamics.

Cerebral cortex (New York, N.Y. : 1991)·2025
Same author

Modification of inhibitory control and craving through transcranial direct current stimulation as an add-on treatment for substance use disorder: protocol for a randomized controlled study.

BMC psychology·2025
Same author

Tracking the cortical processing pathway of representational contents during emotional conflicts.

Journal of neurophysiology·2025
Same journal

Intrinsic Functional Architecture Reflects Individual Differences in Passive Working Memory: An Exploratory Resting-State fMRI Study.

Human brain mapping·2026
Same journal

Symptom Overlap and Neurobiological Similarities Between Posttraumatic Stress Disorder and Tinnitus.

Human brain mapping·2026
Same journal

Test-Retest Reliability of Sensorimotor Activity Measured With Spinal Cord fMRI.

Human brain mapping·2026
Same journal

The Human Visual Claustrum Responses to Physical Stimulus Properties and Subjective Content During Movie Viewing.

Human brain mapping·2026
Same journal

miniMORPH: A Morphometry Pipeline for Low-Field MRI in Infants.

Human brain mapping·2026
Same journal

Reduced Cerebral Blood Flow in the Early Chronic Phase of Recurrent Concussion Among Female Collegiate-Aged Athletes.

Human brain mapping·2026
See all related articles

Related Experiment Video

Updated: Jan 17, 2026

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
09:26

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication

Published on: February 6, 2019

22.0K

Distinct Alpha Connectivity Patterns During Response Inhibition in Alcohol Use Disorder.

Filippo Ghin1, Nasibeh Talebi1, Ann-Kathrin Stock1

  • 1Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Dresden, Germany.

Human Brain Mapping
|September 24, 2025
PubMed
Summary
This summary is machine-generated.

Individuals with alcohol use disorder (AUD) show altered brain connectivity during inhibitory control tasks. Their brains utilize different alpha frequency band networks, particularly when suppressing irrelevant information.

Keywords:
alcohol use disorderalphaeffective connectivitynetwork connectivityresponse inhibitiontheta

More Related Videos

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

1.4K
A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

10.1K

Related Experiment Videos

Last Updated: Jan 17, 2026

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
09:26

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication

Published on: February 6, 2019

22.0K
Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

1.4K
A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

10.1K

Area of Science:

  • Neuroscience
  • Psychiatry
  • Neuroimaging

Background:

  • Alcohol use disorder (AUD) is a chronic condition impacting inhibitory control.
  • The neurophysiological basis of altered inhibitory control in AUD is not fully understood.
  • Investigating brain connectivity dynamics in AUD is crucial for understanding the disorder's impact on cognitive functions.

Purpose of the Study:

  • To investigate neurophysiological mechanisms of directed connectivity in alpha and theta frequency bands during inhibitory control in individuals with AUD.
  • To compare brain connectivity patterns between individuals with AUD and healthy controls.
  • To elucidate how alcohol consumption affects the inhibitory control network.

Main Methods:

  • Electroencephalography (EEG) or similar neuroimaging techniques to measure brain activity.
  • Analysis of directed connectivity in alpha and theta frequency bands.
  • Comparison of neural communication patterns between individuals with AUD and healthy controls during response inhibition tasks.

Main Results:

  • Individuals with AUD and controls exhibit distinct connectivity networks and information transfer mechanisms during response inhibition.
  • AUD group shows altered directional alpha connectivity in key inhibitory control regions under high cognitive load.
  • AUD group demonstrates enhanced medial prefrontal cortex to visual processing connectivity when handling conflicting information, suggesting alpha-mediated suppression of irrelevant stimuli.

Conclusions:

  • Individuals with AUD exhibit altered information transfer within the alpha frequency band during inhibitory control, adapting to different response contexts.
  • Alpha band connectivity differences may underlie the impaired inhibitory control observed in AUD.
  • Theta band connectivity appears less dynamically involved in response inhibition for individuals with AUD compared to controls.