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Blood Collection for Biochemical Analysis in Adult Zebrafish
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Choroidal neovascularization in AZOOR.

Nour Boungab1, Adélaïde Toutee, Youssef Gourinda

  • 1CHNO: Hopital Na4onal des 15-20, Paris, France.

Retinal Cases & Brief Reports
|September 24, 2025
PubMed
Summary
This summary is machine-generated.

Acute zonal occult outer retinopathy (AZOOR) is rare, and choroidal neovascularization is an extremely rare complication. This case highlights multimodal imaging of AZOOR with this complication, successfully treated with anti-VEGF therapy.

Keywords:
AZOORan4-VEGFatrophychoroidal neovascularizationinflamma4onre4na

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Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Medical Imaging

Background:

  • Acute zonal occult outer retinopathy (AZOOR) is a rare retinal disorder with unclear pathogenesis.
  • Choroidal neovascularization (CNV) is an exceptionally uncommon complication of AZOOR.

Purpose of the Study:

  • To document the multimodal imaging characteristics of AZOOR.
  • To report a rare case of AZOOR complicated by CNV.
  • To describe the 18-month follow-up and treatment response.

Main Methods:

  • A 53-year-old female presented with decreased vision and photopsia.
  • Multimodal imaging including fundus examination, autofluorescence, angiography, and OCT-B was performed.
  • The patient received intravitreal anti-VEGF injections for active CNV.

Main Results:

  • Diagnosis of AZOOR was confirmed by clinical examination and imaging.
  • Active choroidal neovascularization was identified in the right macula via OCT-B and angiography.
  • Intravitreal anti-VEGF treatment led to a favorable clinical response.

Conclusions:

  • AZOOR is a rare entity with poorly understood mechanisms.
  • CNV is a very rare complication of AZOOR, presenting unique imaging findings.
  • Multimodal imaging is crucial for diagnosing AZOOR and its complications, with anti-VEGF showing efficacy.