Parotid Castleman's disease: A case report and literature review

This report includes the description of a case of parotid Castleman's disease (CD), along with a review of relevant literature from the last 30 years. The clinical features, pathological classification, clinical diagnosis, treatment modalities, and prognosis of CD have been discussed with the aim of improving clinicians' understanding of its diagnosis and treatment.

The clinical data of one patient with parotid CD were collected, and the related literature was reviewed.

The patient was diagnosed with CD based on pathological and imaging findings. There are two clinical subtypes of CD - unicentric CD (UCD) and multicentric CD (MCD). UCD is further classified into the hyaline-vascular (HV) and plasma cell (PC) types. The patient underwent parotid gland tumor resection under general anesthesia, and has recovered well and remains under regular follow-up.

CD is a rare, benign lymphoproliferative disorder with diverse pathological subtypes. Surgical resection remains the primary treatment. For patients with suboptimal surgical outcomes or contraindications, immunotherapy or chemotherapy are necessary adjunctive treatments. The prognosis of CD is influenced by various factors, including the pathological subtype, but is generally favorable.