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Updated: Jan 17, 2026

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Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
Published on: July 25, 2025
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Ibero-Latin American Consensus on Oblique Lumbar Interbody Fusion (L2-L5): A Modified Delphi Study
Federico Landriel1, Alderico Girão Campos de Barros2, Alejandro Morales Ciancio3
1Neurosurgical Department, Spine Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
World Neurosurgery
|September 24, 2025
Summary
Expert surgeons reached consensus on oblique lumbar interbody fusion at L2/5 (OLIF 25) procedures. This guidance standardizes surgical practice, covering imaging, indications, contraindications, and safety for OLIF 25 in Ibero-Latin America.
Area of Science:
- Spine surgery
- Minimally invasive spine surgery
- Neurosurgery
Background:
- Oblique lumbar interbody fusion (OLIF) is a minimally invasive technique for lumbar spine pathologies.
- Standardized protocols for OLIF 25 are lacking, particularly in the Ibero-Latin American region.
- Expert consensus is crucial for refining surgical techniques and improving patient outcomes.
Purpose of the Study:
- To establish expert consensus on the surgical application of oblique lumbar interbody fusion at the L2/5 spinal level (OLIF 25).
- To develop standardized guidelines for OLIF 25 procedures using a modified Delphi process.
- To provide a framework for consistent OLIF 25 practice in Ibero-Latin America.
Main Methods:
- A modified Delphi process involving 17 experienced spine surgeons from Iberia and Latin America.
- Four rounds of consensus-building, including one face-to-face meeting and three online surveys.
- Consensus defined as ≥70% agreement, with grading of strong (≥90%), moderate (80%-89.9%), and weak (70%-79.9%).
Main Results:
- Consensus was achieved on 45 out of 56 statements (80.4%) across four domains: preoperative assessment, technology/instrumentation, intraoperative considerations, and postoperative care.
- Key agreements included mandatory MRI for corridor assessment, indirect foraminal decompression, and favorable indications for grade I degenerative spondylolisthesis.
- Major contraindications identified were severe canal stenosis with blocked facets and prior ipsilateral retroperitoneal surgery; high-risk steps included pin fixation and retractor opening.
Conclusions:
- This study presents the first Delphi-based regional consensus on OLIF 25.
- The consensus provides structured expert guidance on imaging, indications, contraindications, and intraoperative safety.
- This framework aims to standardize OLIF 25 surgical practice within the Ibero-Latin American region.

