[Symptom changes and rational therapy of vitamin B12 absorption disturbances (author's transl)]

Longterm parenteral therapy with the physiological depot form of vitamin B12 (aquocobalamin) is now the treatment of choice for pernicious anemia and funicular myelopathy. An optimal dosage scheme is given. High-dose oral and intrathecal applications of viatamin B12 are also possible in the individual case. If symptoms of neurological deficiency are already present in funicular myelopathy, additional physiotherapeutic measures, supervision of bladder function, prophylaxis of decubitus ulcers and contractures are necessary.