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Updated: Jan 17, 2026
Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
36-Week personalized resistance training improves muscle function and circulating myokines in older women with
Xian Guo1,2, Guoxia Cao3, Yuting Tang3
1Sport Science School, Beijing Sport University, Beijing, 100084, China. guoxian@bsu.edu.cn.
Background:
This study aims to explore the effects of personalized resistance training on muscle function and serum myokines in possible sarcopenic obese older women.
Methods:
25 possible SO older women were randomly divided into exercise group (n = 13) and control group (n = 12). According to the FITT-VP principle, personalized resistance training programs were developed based on their individual health differences. The training was implemented in three stages with gradually increasing intensity from low to moderate. Each session lasted 40 min, 3 times a week, for a total of 36 weeks. Body composition, muscle function, and serum myokines (irisin, IGF-1, and myostatin) were tested before and after the intervention in both groups.
Results:
The intervention yielded significant between-group improvements in body fat percentage (P < 0.05, Hedges' g = 1.42), ASMI (P < 0.01, Hedges' g = 1.79), HGS (P < 0.01, Hedges' g = 1.91), 6-metre walk speed (P < 0.01, Hedges' g = 1.36), five times sit-to-stand performance (P < 0.05, Hedges' g = 1.08), and TUG (P < 0.01, Hedges' g = 1.20). After 36 weeks, the exercise group also showed higher IGF-1 (P < 0.05, Hedges' g = 1.46) and lower MSTN (P < 0.01, Hedges' g = 1.02) levels compared to controls.
Conclusion:
The 36-week personalized resistance training program results in elevated serum IGF-1 concentrations and reduced myostatin levels, alongside independent improvements in muscle strength and muscle function among older women with probable sarcopenic obesity.
