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Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Obesity and Metabolic Syndrome: Current Insights and Future Directions
Zaiem Zarkasi1, Rajshekhar N Mudaliar1,2, Waseem A Majeed1,2
1Endocrinology, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford, UK.
None:
Obesity and metabolic syndrome are global health challenges, significantly increasing risks for type 2 diabetes, cardiovascular and cerebrovascular diseases, and overall mortality. This narrative review aims to discuss the relationship between obesity and metabolic syndrome; the past, present and future of anti-obesity medications including new advances in incretin-based therapies which have enabled patients to achieve significant weight loss and improvement in metabolic parameters; and the role of metabolic/bariatric surgery which remains the most effective durable treatment for severe obesity, with high remission rates of metabolic comorbidities like type 2 diabetes. Multimodal approaches involving the combination of lifestyle, medical and surgical advances will revolutionise our approach to treating obesity and metabolic syndrome in the future.
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