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07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
768
Risk Factors for Short and Long-Term Mortality in Acute Pulmonary Thromboembolism: A Retrospective Study
Sibel Doruk1, Gulistan Karadeniz2,3, Hüseyin Örün4
1Chest Diseases, Izmir City Hospital, Izmir, Turkiye.
International Journal of General Medicine
|September 25, 2025
Summary
Neutrophil-Lymphocyte Ratio (NLR) predicts survival in acute pulmonary thromboembolism (aPTE), while Platelet-Lymphocyte Ratio (PLR) and age are poor prognostic indicators. Early deep venous thrombosis diagnosis may reduce aPTE mortality.
Area of Science:
- Cardiology
- Hematology
- Pulmonology
Background:
- Acute pulmonary thromboembolism (aPTE) poses a significant mortality risk.
- Predictive markers for aPTE outcomes are crucial for patient management.
Purpose of the Study:
- To evaluate the prognostic value of Neutrophil-Lymphocyte Ratio (NLR) and Platelet-Lymphocyte Ratio (PLR) in aPTE.
- To identify key factors associated with mortality in aPTE patients.
Main Methods:
- Retrospective cohort study of 346 aPTE cases.
- Analysis of mortality at 1 week, 1 month, and 6 months.
- Cox regression analysis to determine prognostic factors.
Main Results:
- Older age, higher ICU admission rates, and lower deep venous thrombosis (DVT) detection were associated with mortality.
- Elevated NLR was linked to mortality in all deceased patients.
- Higher PLR and age were identified as poor prognostic factors for aPTE survival.
Conclusions:
- NLR is a significant prognostic factor for aPTE mortality.
- PLR and age are poor prognostic indicators in aPTE.
- Early detection of DVT may correlate with reduced aPTE mortality.
Keywords:
acute pulmonary thromboembolismmortalityneutrophil-to-lymphocyte ratioplatelet-to-lymphocyte ratioMore Related Videos
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