Idiopathic Eruptive Cherry Angiomatosis: A Case Series of Three Healthy Women

Eruptive cherry angiomatosis (eCA) is a rare clinical diagnosis. The underlying pathophysiology is unknown, but eCA has been associated with medications, lymphoproliferative disease, graft versus host disease, immunosuppression, and human herpesvirus-8. To our knowledge, there have not been previous reports of eCA in healthy female patients. The goal of this case report is to describe the clinical characteristics and present a novel case series of three otherwise healthy adult women and attempt to characterize common features, comparing patient demographics, any associated comorbidities, clinical presentation, and treatment. Three female patients (aged 52, 42, and 38 years) from Southern California were diagnosed with eCA. All three patients were experiencing hormonal fluctuations at the time of onset, including perimenopause and pregnancy. Despite stabilization of their hormonal conditions, their lesions have persisted. Patient A has had her cherry angiomas treated several times with a 595 nm pulse dye laser; however, her lesions have continued to recur. The other two patients have not sought treatment. All patients are in good health without any significant comorbidities.