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Factors Influencing the Availability of Cardiopulmonary Exercise Testing for Patients Undergoing Cardiac
Satoshi Kuhara1, Ryutaro Matsugaki2, Hideaki Itoh3
1Rehabilitation Center of University Hospital University of Occupational and Environmental Health Kitakyushu Japan.
Insights
Cardiopulmonary exercise testing (CPET) use after cardiac resynchronization therapy (CRT) or CRT-defibrillator (CRT-D) implantation is low (3%). Younger age and higher discharge Barthel Index scores were linked to higher CPET rates.
Area of Science:
- Cardiology
- Exercise Physiology
- Medical Device Technology
Background:
- Cardiac resynchronization therapy (CRT) and CRT-defibrillator (CRT-D) are crucial for heart failure management.
- Cardiopulmonary exercise testing (CPET) is a valuable tool for assessing functional capacity in cardiac patients.
- Real-world data on CPET utilization post-CRT/CRT-D implantation is limited.
Purpose of the Study:
- To determine the implementation rate of CPET in patients receiving CRT or CRT-D.
- To identify factors associated with CPET performance in this patient cohort.
- To understand the current landscape of CPET utilization in real-world clinical practice.
Main Methods:
- Analysis of real-world data from Japan's Diagnostic Procedure Combination System (2014-2018).
- Inclusion of 3859 cardiac patients who underwent CRT or CRT-D implantation.
- Statistical analysis including unpaired t-tests, chi-squared tests, and multivariate analysis to identify associated factors.
Main Results:
- CPET was performed in only 3% (134 patients) of the study cohort.
- Patients who underwent CPET were younger and had higher Barthel Index scores at discharge.
- Higher rates of cardiac rehabilitation were observed in patients who received CPET.
Conclusions:
- The implementation rate of CPET following CRT or CRT-D implantation is notably low.
- Factors such as younger age (<70 years) and higher discharge Barthel Index (≥85) are associated with increased CPET utilization.
- In-hospital cardiac rehabilitation emerged as a significant determinant for CPET performance, suggesting a need for integrated care strategies.
Background:
This study aimed to investigate the implementation rate of cardiopulmonary exercise testing (CPET) in patients undergoing cardiac resynchronization therapy (CRT) or cardiac resynchronization therapy-defibrillator (CRT-D), as well as the associated factors, using real-world data.
Methods And Results:
Data from the Diagnostic Procedure Combination System in Japan (2014-2018) was analyzed. The participants were cardiac patients who underwent CRT or CRT-D device implantation (n = 3859). The primary outcome was whether CPET was performed after device implantation. Unpaired t-tests and chi-squared tests were used to compare the characteristics of the CPET (+) and CPET (-) groups. Multivariate analysis was used to identify factors associated with CPET performance. CPET was performed in 134 patients (3%). The CPET (-) group was older and had lower Barthel Index (BI) scores at discharge. CPET (+) patients had a higher rate of cardiac rehabilitation. Multivariate analysis revealed that age < 70 years and BI score ≥ 85 at discharge were associated with CPET implementation. In-hospital cardiac rehabilitation is also an important determinant.
Conclusions:
The CPET implementation after CRT or CRT-D was low. Emphasizing the importance of CPET may improve these rates. Future studies should explore strategies to increase its use in this patient population.
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