Factors Influencing the Availability of Cardiopulmonary Exercise Testing for Patients Undergoing Cardiac

Satoshi Kuhara1, Ryutaro Matsugaki2, Hideaki Itoh3

  • 1Rehabilitation Center of University Hospital University of Occupational and Environmental Health Kitakyushu Japan.

Journal of Arrhythmia
|September 25, 2025
PubMed

Insights

Cardiopulmonary exercise testing (CPET) use after cardiac resynchronization therapy (CRT) or CRT-defibrillator (CRT-D) implantation is low (3%). Younger age and higher discharge Barthel Index scores were linked to higher CPET rates.

Area of Science:

  • Cardiology
  • Exercise Physiology
  • Medical Device Technology

Background:

  • Cardiac resynchronization therapy (CRT) and CRT-defibrillator (CRT-D) are crucial for heart failure management.
  • Cardiopulmonary exercise testing (CPET) is a valuable tool for assessing functional capacity in cardiac patients.
  • Real-world data on CPET utilization post-CRT/CRT-D implantation is limited.

Purpose of the Study:

  • To determine the implementation rate of CPET in patients receiving CRT or CRT-D.
  • To identify factors associated with CPET performance in this patient cohort.
  • To understand the current landscape of CPET utilization in real-world clinical practice.

Main Methods:

  • Analysis of real-world data from Japan's Diagnostic Procedure Combination System (2014-2018).
  • Inclusion of 3859 cardiac patients who underwent CRT or CRT-D implantation.
  • Statistical analysis including unpaired t-tests, chi-squared tests, and multivariate analysis to identify associated factors.

Main Results:

  • CPET was performed in only 3% (134 patients) of the study cohort.
  • Patients who underwent CPET were younger and had higher Barthel Index scores at discharge.
  • Higher rates of cardiac rehabilitation were observed in patients who received CPET.

Conclusions:

  • The implementation rate of CPET following CRT or CRT-D implantation is notably low.
  • Factors such as younger age (<70 years) and higher discharge Barthel Index (≥85) are associated with increased CPET utilization.
  • In-hospital cardiac rehabilitation emerged as a significant determinant for CPET performance, suggesting a need for integrated care strategies.
Abstract

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