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Updated: Jan 17, 2026

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Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
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How can children benefit from total-body PET?
Paul J H van Snick1, Sasha O V Ivashchenko1, Joyce van Sluis1
1Department of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University Medical Center Groningen, University of Groningen, the Netherlands.
The British Journal of Radiology
|September 25, 2025
Summary
Long axial field-of-view (LAFOV) PET/CT scanners enhance paediatric nuclear medicine by improving image quality and reducing radiation doses. These advanced systems offer faster, more comfortable whole-body scans for children, aligning with the ALARA principle.
Area of Science:
- Nuclear Medicine
- Medical Imaging
- Paediatric Diagnostics
Background:
- Paediatric nuclear medicine faces challenges with radiation sensitivity and procedural compliance in children.
- Traditional PET/CT scanners have limitations in scan time and radiation dose, impacting young patients.
- Long axial field-of-view (LAFOV) PET/CT technology offers potential solutions to these paediatric imaging issues.
Purpose of the Study:
- To review the technical advancements of LAFOV PET/CT systems.
- To explore the expanding role and clinical advantages of LAFOV PET/CT in paediatric imaging.
- To address the opportunities and challenges associated with implementing LAFOV PET/CT in children.
Main Methods:
- Review of technical specifications and clinical applications of LAFOV PET/CT scanners.
- Analysis of benefits including enhanced sensitivity, reduced radiopharmaceutical doses, and shorter scan times.
- Discussion of whole-body imaging capabilities and impact on motion artefacts and patient comfort.
Main Results:
- LAFOV PET/CT provides superior image quality with significantly reduced radiation exposure and scan durations.
- Whole-body imaging in a single position minimizes motion artefacts, enhancing patient experience and reducing anxiety.
- The technology supports personalized imaging protocols, aligning with the ALARA principle for paediatric radiation safety.
Conclusions:
- LAFOV PET/CT represents a significant advancement in paediatric nuclear medicine, improving diagnostic capabilities.
- The technology overcomes limitations of conventional scanners, enabling safer, faster, and more comprehensive paediatric assessments.
- Despite initial costs, LAFOV PET/CT promises to transform paediatric diagnostics through enhanced imaging and patient-centered care.
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