Checklist-Guided Code Status Discussions in Patients for Whom Cardiopulmonary Resuscitation Is Considered Futile: An

Armon Arpagaus1,2, Leta Arpagaus1, Christoph Becker1,3

  • 1Division of Medical Communication/Psychosomatic Medicine, University Hospital Basel, Basel, Switzerland.

JAMA Network Open
|September 25, 2025
PubMed

Insights

Structured code status discussions using a checklist reduced ICU admission preferences in futile cardiopulmonary resuscitation (CPR) patients. This approach also eased physician challenges without negatively impacting patient psychological burden.

Area of Science:

  • Medical Ethics
  • Clinical Communication
  • Palliative Care

Background:

  • Code status discussions are crucial for advanced care planning but pose challenges for clinicians when cardiopulmonary resuscitation (CPR) is considered futile.
  • Effective communication strategies are needed to navigate these complex discussions.

Purpose of the Study:

  • To evaluate the impact of a structured communication approach on code status decisions and quality-of-care measures in patients with futile CPR.
  • To assess the effect on patients' psychological burden and physicians' perceptions of the discussions.

Main Methods:

  • The GUIDE trial was a multicenter randomized clinical trial involving medical inpatients with futile CPR (GOAL-7 score ≥14 or CFS score ≥7).
  • Patients were randomized to either a checklist-guided discussion or usual care.
  • Outcomes included code status, preference for mechanical ventilation and ICU admission, patient psychological burden, and physician perceptions.

Main Results:

  • A total of 177 patients were studied; 85% had do-not-resuscitate orders.
  • No significant difference in do-not-resuscitate orders between groups (89% vs 82%).
  • Patients in the checklist group showed a reduced preference for ICU admission (36% vs 52%, P=.046) and physicians found discussions less challenging (P=.006).
  • No significant difference in patients' psychological burden was observed.

Conclusions:

  • Checklist-guided code status discussions effectively reduce ICU admission preferences in patients with futile CPR.
  • This structured approach alleviates physician challenges during these discussions.
  • The intervention does not adversely affect patients' psychosocial burden, supporting its clinical relevance.
Abstract

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