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Updated: Jul 15, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
[Microaxial Flow Pump( Impella):Clinical Evidence and Guideline]
1Department of Cardiovascular Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan.
Abstract:
The Impella is a catheter-based microaxial flow pump that is inserted through a small vascular graft (Impella 5.5) or directly from femoral artery (Impella CP) and placed across the aortic valve. By draining blood from the left ventricle and pumping it to the ascending aorta, the device not only increases cardiac output, but also unloads the left ventricle which facilitates recovery of damaged cardiac muscles. It has been used in more than 14,000 cardiogenic shock patients in Japan and excellent clinical outcomes have been published in more than 20 major journals in the last three years using J-PVAD registry which is a mandatory national database. New evidences and guidelines may upgrade the value of this device as a less invasive left ventricular unloading device even more in the near future.

