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Updated: Jul 3, 2026

Optimization of Laser-Capture Microdissection for the Isolation of Enteric Ganglia from Fresh-Frozen Human Tissue
Published on: June 14, 2018
[Intersegmental Dissection Using Microwave Energy]
Toshiteru Nagashima1, Yoichi Ohtaki
1Division of General Thoracic Surgery, Integrative Center of General Surgery, Gunma University, Maebashi, Japan.
Abstract:
Lung segmentectomy for small peripheral lung cancers has been increasingly performed in recent years. A critical step in this procedure is the intersegmental plane dissection, which, if not performed properly, may lead to complications such as prolonged air leakage. Traditionally, electrocautery and staplers have been commonly used for this purpose. In this report, we describe our experience using a domestically developed microwave surgical instrument. This device utilizes 2,450 MHz microwave energy to vibrate water molecules within tissue, creating a uniform coagulation layer while keeping tissue temperatures below 100 ℃. This allows for effective sealing of the lung parenchyma. Additionally, its scissor-like shape enables intuitive and precise handling during dissection. Our initial experience demonstrated minimal intraoperative bleeding and a low rate of postoperative complications. These results suggest that the microwave surgical device may offer a safe and effective alternative for lung parenchymal dissection in segmentectomy. Its ability to create a consistent seal without excessive thermal damage may help improve surgical outcomes and reduce postoperative morbidity. This technique could be particularly useful in cases requiring precise anatomical dissection, supporting its broader adoption in thoracic surgery.
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