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Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
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Gastric leiomyosarcoma mimicking hepatocellular carcinoma
Himanshu Gupta1, D S Darshanik1, Ritambara Nada2
1GI Surgery, HPB and Liver Transplantation, PGIMER, Chandigarh, India.
BMJ Case Reports
|September 25, 2025
Summary
Gastric leiomyosarcoma, a rare cancer, presents with vague symptoms. Diagnosis requires endoscopic ultrasound-guided biopsy, crucial for differentiating it from liver tumors and guiding treatment.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Medical Diagnostics
Background:
- Gastric leiomyosarcoma is a rare and aggressive malignancy.
- Early diagnosis is challenging due to non-specific gastrointestinal symptoms.
Purpose of the Study:
- To present a case of gastric leiomyosarcoma.
- To highlight diagnostic challenges and the importance of preoperative biopsy.
Main Methods:
- Case report of a middle-aged male patient.
- Diagnostic workup included imaging and endoscopic ultrasound-guided biopsy.
- Intraoperative findings confirmed gastric origin.
Main Results:
- Initial radiographic evaluation suggested a liver tumor (hepatocellular carcinoma).
- Preoperative biopsy and immunostaining were essential for accurate diagnosis.
- The tumor was confirmed to be of gastric origin during surgery.
Conclusions:
- Accurate preoperative diagnosis of gastric leiomyosarcoma is critical.
- Endoscopic ultrasound-guided biopsy is the gold standard for diagnosis.
- Differentiating gastric tumors from liver malignancies requires a multidisciplinary approach.
