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Updated: Jan 16, 2026
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Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles
Published on: March 6, 2016
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High-energy-density acoustofluidic device using a double-parabolic ultrasonic transducer
Enrico Corato1, Ola Jakobsson1, Wei Qiu1
1Department of Biomedical Engineering, Lund University, Lund, Sweden.
Physical Review Applied
|September 26, 2025
Summary
We developed a novel mechanical interface for acoustofluidic devices, enabling high acoustic energy density for clinical applications. This technology successfully focuses particles in microfluidic chips, advancing biomedical applications.
Area of Science:
- Acoustofluidics
- Biomedical Engineering
- Mechanical Engineering
Background:
- High-acoustic-energy-density acoustofluidic devices are crucial for clinical biomedical applications.
- Existing technologies require improved methods for delivering acoustic fields within microfluidic systems.
Purpose of the Study:
- To present a mechanical interface for generating high-amplitude acoustic fields in microfluidic chips.
- To experimentally characterize and simulate a double-parabolic metallic acoustic waveguide.
Main Methods:
- Utilizing two large piezoelectric elements to translate vibrations into a microfluidic chip.
- Conducting experimental characterization and 2D simulations of a double-parabolic acoustic waveguide.
- Employing laser-Doppler vibrometer measurements for validation.
Main Results:
- Successfully focused 4.9-μm polystyrene particles at a flow rate of 5 ml/min.
- Achieved high acoustic energy densities: average 1207 J/m³, maximum 2977 J/m³ at 1.5 W input power.
- Confirmed the significant role of transverse sound waves in the waveguide's mechanism.
Conclusions:
- The developed mechanical interface effectively delivers high acoustic energy density to microfluidic devices.
- The double-parabolic waveguide design shows promise for acoustofluidic applications.
- Transverse sound waves are key to the waveguide's performance, guiding future design optimizations.
