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Updated: Jan 16, 2026

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FSH-secreting Giant Pituitary Macroadenoma With Aggressive Clinical Behavior

Melina I Manolas1, Zoe M Videlefsky2, Janaki M Samavedam3

  • 1Department of Internal Medicine, Division of Endocrinology, Diabetes, & Metabolism, Weill Cornell Medical College, New York, NY 10021, USA.

JCEM Case Reports
|September 26, 2025
PubMed
Summary

Functional gonadotroph adenomas (FGAs) can present challenging clinical courses, with aggressive growth despite low-grade histology. This case highlights the need for advanced prognostic markers and multimodal therapy for refractory FGAs.

Keywords:
aggressive pituitary tumorsfunctional gonadotroph adenomapituitary adenoma

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