Analysis of Dermal Thickness Across 10 Areas and Injection Depth After Polynucleotide Injection Using Rejumate...

Area of Science:

• Aesthetic Medicine
• Dermatology
• Medical Device Technology

Background:

• Automated injection devices are increasingly vital in aesthetic medicine for precise treatments like polynucleotide (PN) injections.
• This study investigates dermal thickness variations and the injection consistency of the Rejumate automatic injector.

Purpose of the Study:

• To analyze dermal thickness across 11 facial regions.
• To evaluate the consistency and precision of injection depth achieved by the Rejumate automatic injector for PN delivery.

Main Methods:

• Dermal thickness was measured using high-resolution ultrasound in 31 patients across 11 facial areas.
• A standardized 2-mL PN injection was administered using the Rejumate injector, with injection depth analyzed across 317 points.

Main Results:

• Average dermal thickness varied from 0.53 mm (lower eyelid) to 1.18 mm (temple/posterior cheek).
• The Rejumate injector achieved a consistent average injection depth of 0.55 mm (SD=0.13 mm) with minimal depth variability (IQR=0.17 mm).

Conclusions:

• The Rejumate automatic injector provides reliable and controlled depth delivery of PN, crucial for aesthetic treatments.
• This precision enhances safety and efficacy, offering a valuable tool for optimizing outcomes and patient satisfaction in skin rejuvenation.