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Updated: Jan 16, 2026

Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution
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RiboCop surveils pre-rRNA processing by Dicer in cellular quiescence

B Roche1,2, R A Martienssen1

  • 1Cold Spring Harbor Laboratory; 1 Bungtown Road, Cold Spring Harbor, NY, USA.

Biorxiv : the Preprint Server for Biology
|September 26, 2025
PubMed
Summary

Researchers discovered a new RNA molecule, RiboCop, that silences ribosomal DNA (rDNA) in quiescent cells. This process is crucial for maintaining cellular homeostasis during dormancy by preventing the production of non-functional ribosomal RNA.

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