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Case Report: NUTM1-rearranged lung sarcoma: a rare case imaged with dynamic and static 18F-FDG PET/CT
Xieraili Wumener1, Xiaoxing Ye2, Jiuhui Zhao1
1Department of Nuclear Medicine, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College/Shenzhen Clinical Research Center for Cancer, Shenzhen, China.
Background:
Nuclear protein of testis midline carcinoma family member 1 (NUTM1)-rearranged lung sarcomas are rare malignant malignancies. 18F-fluorodeoxyglucose (FDG) positron emission tomography/CT (PET/CT) is widely used for the differential diagnosis and staging of malignant tumours. This study aimed to identify the static and dynamic features of 18F-FDG PET/CT in NUTM1-rearranged lung sarcomas.Case Description: A 46-year-old male patient underwent a chest CT scan for trauma, which revealed a tumor in the hilum of the left lung. The patient also underwent dynamic (chest) and static (whole body) PET/CT scans. The dynamic and static 18F-FDG PET/CT scans showed a tumor in the hilum of the left lung, with a size of 8.6×6.7 cm, an SUVmax of 17.6 and a Ki of 0.0668 ml/g/min. Final pathology and genetic testing confirmed NUTM1-rearranged lung sarcoma.
Conclusions:
This case shows dynamic and static 18F-FDG PET/CT and pathological features of NUTM1-rearranged lung sarcomas.
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