Secondary Perianal Paget's Disease Originating From Adenocarcinoma of the Anorectal Junction: A Case Report
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Updated: Jan 16, 2026

Surgical Robot-Assisted Transanal Specimen Extraction Radical Sigmoidectomy Without an Auxiliary Abdominal Incision
Published on: June 13, 2025
Jun He1, Rong-Chao He2, Jian-Zhong Peng3
1Department of Colorectal Surgery, Hangzhou Third People's Hospital, Hangzhou, Zhejiang, People's Republic of China.
Abstract:
Secondary extramammary Paget's disease (EMPD), originating from the cutaneous dissemination of malignant cells, represents a rare subtype prone to misdiagnosis. This study presents a case of secondary perianal Paget's disease (PPD) associated with adenocarcinoma at the anorectal junction. Preoperative full-thickness mapping biopsy was utilized for the assessment of lesion margins. The patient demonstrated favorable postoperative recovery following a multimodal therapeutic regimen.
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