Trichological disorders in organ transplant recipients (OTRs): a literature review

Area of Science:

• Nephrology
• Dermatology
• Transplantation Medicine

Background:

• Kidney transplantation is a preferred treatment for end-stage renal disease, improving patient outcomes.
• Immunosuppressive therapy post-transplantation is associated with various side effects, including dermatological issues.
• Hair disorders (trichological problems) post-transplantation are less explored compared to cutaneous malignancies.

Purpose of the Study:

• To review existing literature on trichological problems in kidney transplant recipients.
• To explore the correlation between immunosuppressive medications and hair disorders.
• To highlight the discrepancy in perceived and reported alopecia rates.

Main Methods:

• Systematic literature review of trichological complications in transplant recipients.
• Analysis of studies correlating immunosuppressive drugs with hair disorders.
• Synthesis of patient-reported outcomes versus physician observations.

Main Results:

• A significant underestimation of alopecia prevalence exists between patient reports and physician perceptions.
• Certain immunosuppressive drugs are linked to various hair disorders.
• Trichological complications significantly impact patient quality of life, particularly for women and adolescents.

Conclusions:

• There is a need for increased awareness and recognition of hair disorders in transplant patients.
• Further research is essential to understand the prevalence, mechanisms, and effective management of these complications.
• Addressing trichological issues can enhance overall patient care and well-being post-transplantation.