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Precision medicine requires precision proteomics: discordance between proteomic and clinical assays in UK Biobank

Bhawana Singh1, Ioanna Tzoulaki2,3, Manuel Mayr1,4

  • 1National Heart and Lung Institute, Imperial, 86 Wood Lane, London W12 0BZ, UK.

Cardiovascular Research
|September 26, 2025
PubMed
Abstract

No abstract available in PubMed .

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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