Comparison of Allergic Rhinitis Treatments on Patient Satisfaction: A MASK-air and EAACI Methodological Committee...

Area of Science:

• Allergy and immunology
• Pharmacology
• Digital health

Background:

• Patient satisfaction with treatments is crucial for medication adherence and usage patterns.
• Understanding satisfaction and co-medication frequency can inform treatment guidelines for allergic rhinitis (AR).

Purpose of the Study:

• To compare different allergic rhinitis (AR) medications based on patient satisfaction.
• To assess the frequency of co-medication use for various AR treatments.

Main Methods:

• Utilized data from the mHealth app MASK-air, assessing 28,177 days of medication use from 1691 users.
• Employed multivariable regression models to compare treatment satisfaction (VAS satisfaction) and co-medication odds for different AR medication classes.
• Analyzed intranasal corticosteroids (INCS), intranasal antihistamines (INAH), fixed INAH+INCS combinations, and oral antihistamines (OAH).

Main Results:

• Co-medication use was associated with lower treatment satisfaction across all analyzed medication classes.
• Oral antihistamines (OAH) showed lower satisfaction in monotherapy compared to INCS and INAH+INCS.
• Intranasal corticosteroids (INCS) had higher odds of co-medication use compared to OAH and INAH+INCS.

Conclusions:

• Patient-reported data reveals significant differences in satisfaction and co-medication frequency among AR treatments.
• Findings highlight the importance of patient satisfaction in AR treatment selection and adherence.
• Results offer valuable insights for refining AR treatment guidelines and improving patient care.