Related Experiment Video For LC‐OCT
Updated: Jan 16, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Yellow Nested Melanoma: Line-Field Confocal Optical Coherence Tomography and Literature Review
Bettolini Luca1, Maione Vincenzo1, Carugno Andrea2
1Dermatology Department, University of Brescia, ASST Spedali Civili di Brescia, Brescia, Italy.
Abstract:
Nested melanoma, a relatively new subtype of melanoma first reported in 2012, is characterised by neoplastic cells organised into nests. We present a unique case of yellow nested melanoma, detailing its clinical, dermoscopic, RCM, and, for the first time to our knowledge, LC-OCT features. Alongside a comprehensive review of the literature, our findings challenge the traditional associations with advanced age and sun-damaged skin, advocating for the term 'nested melanoma' to better reflect its characteristics.
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