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Recent Advances in Flexible Materials for Wearable Optical Biosensors
Linyan Xie1,2,3, Kai Yang1,2, Mengfei Wang1,2
1School of Mathematical Medicine and School of Medical Engineering, Henan Medical University, Xinxiang 453003, China.
Biosensors
|September 26, 2025
Summary
Flexible optical biosensors integrate advanced materials for personalized health monitoring. These wearable devices offer promising early disease diagnostics and continuous physiological tracking, revolutionizing healthcare.
Area of Science:
- Materials Science
- Biomedical Engineering
- Optical Sensing Technologies
Background:
- Wearable optical biosensors are advancing personalized medicine and disease prevention.
- Flexible materials are crucial for enhancing sensor functionality, sensitivity, and adaptability.
Purpose of the Study:
- To review recent advancements in flexible materials for wearable optical biosensors.
- To explore optical sensing mechanisms and their role in biomarker detection.
- To identify challenges and future directions for practical deployment.
Main Methods:
- Review of flexible materials (polymers, nanostructures, MXenes, hydrogels, textiles).
- Exploration of optical sensing mechanisms (SPR, optical fiber, fluorescence, chemiluminescence, SERS).
- Analysis of challenges in fabrication, stability, biocompatibility, and signal interference.
Main Results:
- Flexible materials significantly improve wearable sensor performance.
- Various optical sensing techniques enhance detection of biomarkers and physiological parameters.
- Key challenges include long-term stability, biocompatibility, and minimizing signal interference.
Conclusions:
- Flexible optical biosensors show great promise for personalized health management and early disease diagnosis.
- Future research should focus on multifunctional, miniaturized, and resilient devices with intelligent data integration.
- Innovations will accelerate clinical adoption and revolutionize healthcare.
