Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetic Models: Comparison and Selection Criterion01:26

Pharmacokinetic Models: Comparison and Selection Criterion

Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play.
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In Vitro Antitumor Effects of Melittin Attached to Fe<sub>3</sub>O<sub>4</sub> Magnetic Nanoparticles with Synergistic Contribution of Magnetic Hyperthermia.

Molecules (Basel, Switzerland)·2026
Same author

Structure-Biomedical Activity Relationship of Tunable Ceria-Graphene Nanocomposites Leading to Divergent Cellular Responses.

International journal of molecular sciences·2026
Same author

Pharmacological Properties and the Impact of Caffeic Acid-Entrapped Liposomes on Triple-Negative Breast Cancer Cell Lines Exposed to Doxorubicin.

Antioxidants (Basel, Switzerland)·2026
Same author

Green-Synthesized Rutin-Capped Gold Nanoparticles Attenuate Experimental Liver Fibrosis by Targeting Oxidative Stress and TGF-β Signaling.

Nanomaterials (Basel, Switzerland)·2026
Same author

Molecular Mechanisms, Dynamic Lesions, and Therapeutic Targets in Intestinal Ischemia-Reperfusion Injury: A Systematic Review.

International journal of molecular sciences·2026
Same author

Characterization of Newly Synthesized Nanobiomaterials for the Treatment of White Spot Lesions.

Biomolecules·2026

Related Experiment Video

Updated: Jul 23, 2026

The Polyvinyl Alcohol Sponge Model Implantation
06:23

The Polyvinyl Alcohol Sponge Model Implantation

Published on: April 18, 2012

20.2K

Biological Models for Evaluating Hydrogel-Based Formulations in Wound Healing.

Ioana Baldea1, Ioana Georgeta Grosu2, Sahar Ghafury1

  • 1Department of Physiology, University of Medicine and Pharmacy, Clinicilor 1, 400006 Cluj-Napoca, Romania.

Gels (Basel, Switzerland)
|September 26, 2025
PubMed
Summary

Hydrogels are advanced wound dressings that accelerate healing by mimicking the skin's natural barrier. Innovations in hydrogel technology promise better wound care and reduced healthcare costs.

Keywords:
burn wound modelcrosslinked hydrogelsfull-thickness skin modelhydrogel-based dressingsreconstructed human epitheliumscratch assaysurgical wound modelwound healing models

More Related Videos

Murine Model of Wound Healing
05:39

Murine Model of Wound Healing

Published on: May 28, 2013

67.2K
Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.
09:06

Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.

Published on: March 25, 2020

9.9K

Related Experiment Videos

Last Updated: Jul 23, 2026

The Polyvinyl Alcohol Sponge Model Implantation
06:23

The Polyvinyl Alcohol Sponge Model Implantation

Published on: April 18, 2012

20.2K
Murine Model of Wound Healing
05:39

Murine Model of Wound Healing

Published on: May 28, 2013

67.2K
Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.
09:06

Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.

Published on: March 25, 2020

9.9K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • The skin acts as a vital barrier and regulates physiological functions.
  • Wound healing is a complex biological process involving distinct stages.
  • Hydrogels offer superior moisture retention and biocompatibility for wound dressings.

Purpose of the Study:

  • To review hydrogel types and their classification.
  • To evaluate hydrogels in various experimental wound healing models.
  • To discuss the clinical applications of hydrogels in wound therapy.

Main Methods:

  • Classification of hydrogels based on origin, crosslinking, and responsiveness.
  • Evaluation of hydrogels in in vitro, ex vivo, and in vivo models.
  • Review of clinical studies on hydrogel-based wound dressings.

Main Results:

  • Hydrogels exhibit high moisture retention and biocompatibility.
  • Hydrogels effectively support accelerated wound healing and drug delivery.
  • Semisynthetic and stimuli-responsive hydrogels show enhanced therapeutic potential.

Conclusions:

  • Hydrogels represent a promising class of wound dressings.
  • Advances in hydrogel design and testing models improve therapeutic outcomes.
  • Continued innovation is crucial for optimizing wound care and reducing healthcare burdens.