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Related Concept Videos

Restorative Care01:19

Restorative Care

2.3K
Restorative care is provided once a patient has been discharged from a healthcare facility and requires additional services. The additional services include home care, rehabilitation programs, and extended care. Restorative care centers help the patient regain their previous level of functioning or acquire a new level of functioning due to the incapacitating effects of a disease or a disability. It aims to assist patients in enhancing their quality of life by encouraging independence,...
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Related Experiment Video

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Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material
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Innovative Smart Materials in Restorative Dentistry.

Roxana Ionela Vasluianu1, Livia Bobu2, Iulian-Costin Lupu1

  • 1Department of Prosthodontics, Faculty of Dental Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.

Journal of Functional Biomaterials
|September 26, 2025
PubMed
Summary

Smart dental materials like bioactive glass ceramics and silver nanoparticle polymers offer advanced solutions for biofilm infections. These innovations promise self-defending restorations with enhanced tissue regeneration and infection control.

Keywords:
antibacterialbioactivebioactive glasschitosanoral medicinepH-responsiverestorative dentistrysilver nanoparticlesmart materialsstimuli-responsive

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Area of Science:

  • Biomaterials Science
  • Dental Materials
  • Nanotechnology

Background:

  • Biofilm-associated infections pose a significant challenge in restorative dentistry.
  • Existing dental materials often lack sufficient antimicrobial and regenerative properties.

Purpose of the Study:

  • To review smart bioactive and antibacterial materials for transforming restorative dentistry.
  • To highlight materials with potential for self-defending dental restorations.

Main Methods:

  • Review of literature on bioactive glass ceramics (BGCs), silver nanoparticle (AgNP)-doped polymers, and pH-responsive chitosan coatings.
  • Analysis of emerging innovations including quaternary ammonium compounds, graphene oxide hybrids, and 4D-printed hydrogels.

Main Results:

  • BGCs demonstrated >90% biofilm reduction and promoted bone integration.
  • AgNP-polymers effectively inhibited S. mutans and C. albicans with controlled dosing (<0.3 wt% in PMMA) to prevent cytotoxicity.
  • Chitosan coatings facilitated pH-triggered drug release to disrupt biofilms.

Conclusions:

  • Smart materials offer promising avenues for self-defending dental restorations, merging infection control with tissue regeneration.
  • Clinical translation requires addressing cytotoxicity, standardizing antibiofilm testing, and ensuring long-term efficacy.
  • Future research may involve AI-driven design for multifunctional, immunomodulatory dental solutions.