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Optimized detection of ESBL producers, carbapenemase producers, and VRE from rectal swabs using enrichment broth for
Dominique S Blanc1,2,3, Massiha Kamyar4, Patrice Nordmann5,6
1Infection Prevention and Control Unit, Infectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. dominique.blanc@chuv.ch.
Abstract:
This study evaluates the added value of using enrichment broths for improving the detection of multidrug-resistant (MDR) bacteria-VRE, ESBL producers, and carbapenemase-producing organisms (CPOs)-from rectal swabs. Comparing direct plating to enrichment-based methods significantly increased detection sensitivity, especially for CPOs (from 17 to 27 cases, a 58.8% increase). Detection rates for ESBL producers and VRE also improved significantly (by 20%). Pre-enrichment is therefore a valuable addition to routine MDR bacteria screening protocols, which is particularly useful when high accuracy is needed for prevention and infection control as well as for outbreak management.
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