Related Experiment Video
Updated: Jan 16, 2026
05:55
High-throughput, Microscale Protocol for the Analysis of Processing Parameters and Nutritional Qualities in Maize Zea mays L.
Published on: June 16, 2018
7.4K
Functional factors for precision nutrition interventions in starch-based delivery systems
Mengyuan Qin1,2, Lingjin Li1,2,3, Jing Du4
1School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu Province, PR China.
Critical Reviews in Food Science and Nutrition
|September 26, 2025
Summary
Starch-based delivery systems offer enhanced bioavailability for functional factors in precision nutrition. These customizable systems show promise for managing chronic diseases like diabetes and cancer.
Area of Science:
- Biomaterials Science
- Nutritional Science
- Drug Delivery Systems
Background:
- Chronic diseases (diabetes, cardiovascular, cancer) present global health challenges.
- Precision nutrition aims to manage these conditions by delivering tailored functional factors.
- Starch-based delivery systems offer biocompatibility, biodegradability, and tunable properties for enhanced efficacy.
Purpose of the Study:
- To comprehensively analyze starch-based delivery systems for precision nutrition.
- To examine biological barriers to oral delivery and how starch carriers overcome them.
- To highlight applications and potential in managing chronic diseases.
Main Methods:
- Review of literature on starch-based carriers (nanoparticles, microcapsules, hydrogels).
- Analysis of engineering strategies to overcome oral delivery barriers.
- Examination of targeted delivery applications for functional factors.
Main Results:
- Starch-based systems improve stability, bioavailability, and targeted delivery of functional factors.
- Engineered carriers effectively address biological barriers for oral administration.
- Demonstrated potential in managing inflammatory bowel disease, diabetes, and cancer.
Conclusions:
- Starch-based delivery systems are crucial for advancing precision nutrition.
- These systems offer customizable solutions for personalized nutrition and chronic disease management.
- Significant potential exists for future trends and applications in this field.
More Related Videos
Related Concept Videos
01:28Factors Influencing Drug Absorption: Pharmaceutical Parameters
403
Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
403
01:05Bioavailability Enhancement: Drug Stability Enhancement and GI Retention
200
Body:Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
200
01:22Biopharmaceutical Factors Influencing Drug Product Design: Overview
233
Rational drug product design integrates knowledge of the drug’s physicochemical properties, formulation components, manufacturing techniques, and intended route of administration. Each factor influences the drug’s performance, including how it is released, absorbed, and eliminated in the body.The physicochemical properties of a drug—such as solubility, stability, and particle size—affect its compatibility with excipients and the choice of dosage form. Excipients, though...
233
01:20Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry
505
Orally administered drugs primarily enter the systemic circulation via passive diffusion through the intestinal membranes. The drug's absorption is influenced by drug stability in the gastrointestinal GI tract, membrane permeability, the surface area available for absorption, luminal drug concentration, and residence time in the lumen. Drug permeability can be enhanced by adjusting the lipophilicity, polarity, or molecular size of the drug, promoting its passive transport across intestinal...
505
01:22Factors Influencing Drug Absorption: Physicochemical Parameters
820
The physicochemical characteristics of drugs play a crucial role in formulating stable and bioavailable drug products. The solubility of a drug, governed by the varying pH along the GI tract and its dissociation constant (pKa), is pivotal in determining its ionization state and absorption rate. Notably, weak acids and bases remain unionized and are absorbed more rapidly.
Enhanced drug absorption can be achieved by reducing particle sizes and increasing surface areas, thereby facilitating...
Enhanced drug absorption can be achieved by reducing particle sizes and increasing surface areas, thereby facilitating...
820
01:23Factors Affecting Dissolution: Particle Size and Effective Surface Area
1.6K
Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
1.6K