Caring Text Messages for Suicide Prevention in Urban American Indian Youth: Protocol for a Randomized Controlled...

American Indian (AI) young adults in urban areas have many cultural strengths but also face unique challenges. Cultural norms within their communities strongly emphasize relationships. Previous research has found that receiving occasional positive and nondemanding messages-caring text messages-can be beneficial among people experiencing suicidality.

To ameliorate increasing rates of suicide and suicidality among AI young adults, we implemented a caring text message intervention designed to increase social connectedness.

This 2-arm, double-blinded, randomized controlled trial is being implemented at 2 clinical sites with large AI populations. Partnering with clinics in Albuquerque, New Mexico, and Rapid City, South Dakota, we are recruiting AI adults aged 18-34 years to participate in a caring text message study. During the baseline visit, participants complete several surveys and an interview with study staff to understand their history of suicidal behavior. After completion of the baseline visit, participants are randomized to receive the intervention-approximately 30 caring text messages-or treatment as usual. The text messaging platform selected for this study allows bidirectional messaging; while there is no expectation that participants respond, they can provide feedback or seek additional resources. Participants are followed up at 6 and 12 months postbaseline. At the final 12-month follow-up visit, they complete many of the same surveys and participate in an interview to ascertain suicidality since their initial visit. The primary outcomes of interest are suicide-related behaviors-suicidal ideation, suicide planning, suicide attempt, or thoughts and actions requiring hospitalization. Secondary outcomes include social connectedness and other measures of mental health. We will use an intention-to-treat analysis with logistic and linear regression to calculate odds ratios and risk differences (95% CIs) for binary and continuous outcomes.

As of June 2025, the New Mexico site has finished recruitment and follow-up assessments. The South Dakota site is still enrolling participants and has conducted the first follow-up assessments. The project has been well-received by participants.

This randomized controlled trial will evaluate whether a caring text message intervention is effective in reducing suicidality among AI young adults in urban areas. Participants have received the culturally tailored caring text messages. This trial will help establish whether caring text messages are an effective strategy for reducing suicidal behaviors and promoting feelings of connectedness among AI young adults.

ClinicalTrials.gov NCT03136094; http://clinicaltrials.gov/show/NCT03136094.

DERR1-10.2196/71344.