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Terahertz asynchronous twin-comb for prefiguring hypersensitivity beyond spectrum domain.

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This study introduces a novel terahertz asynchronous twin-comb sensor for ultrasensitive biochemical detection. This advanced sensor achieves significantly enhanced sensitivity, enabling trace detection and photoactive material applications.

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Area of Science:

  • Terahertz (THz) spectroscopy
  • Advanced optical sensing technologies

Background:

  • Terahertz (THz) regime offers low photon energy for biochemical sensing.
  • Existing THz biosensing methods face inherent sensitivity limitations.

Purpose of the Study:

  • To develop a terahertz asynchronous twin-comb sensor with an extra-spectrum sensing mechanism.
  • To significantly enhance sensitivity for biochemical detection beyond existing limits.

Main Methods:

  • Utilized a terahertz asynchronous twin-comb sensor.
  • Implemented an extra-spectrum sensing mechanism via cascading microchannels within a metallic waveguide.
  • Investigated photoisomerization of azo dye in the terahertz band.

Main Results:

  • Achieved an enhanced sensitivity of 4 orders of magnitude compared to existing terahertz biosensing.
  • Demonstrated hypersensitivities of 0.398 GHz mm² pg⁻¹ in trace detection.
  • Observed a photoresponse sensitivity of 0.91 GHz cm² mW⁻¹ for azo dye photoisomerization.

Conclusions:

  • Instantiated an asynchronous twin-comb sensing approach beyond the spectrum domain for ultrasensitive detection.
  • Opened possibilities for photoactive material-assisted terahertz sensors.
  • Promised applications in optical frequency comb precision metrology, AI photonics, and integrated sensing and communications.